While you can do everything through a sequence of different clicks, keyboard shortcuts are a great way to get things done a little faster. Most keyboard shortcuts work not only in Windows Explorer, but also in many other programs.
General Shortcuts:
Cut out
Copy
Paste
Undo
Redo
Shut down / Task manager menu
Task manager
CTRL + X
CTRL + C
CTRL + V
CTRL + Z
CTRL + Y
CTRL + ALT + DEL
CTRL + SHIFT + ESC